Magnolia Serum - Powerful anti-wrinkle serum

That

Magnolia Serum - Powerful anti-wrinkle serum

Our new serum found here!

And among its ingredients, we find:

Gotu kola - Centella asiatica

Centella asiatica, also known as gotu kola, is a popular medicinal plant widely used in the Orient to treat infectious skin diseases and accelerate the healing of skin ulcers and wounds. Its active compounds include pentacyclic triterpenes, primarily asiaticoside, madecosside, asiatic acid, and madecassic acid. ¹

A study investigating the potential application of madecassoside for medical and cosmetic purposes to protect the skin focused on its anti-inflammatory and skin moisturizing activities related to Propionibacterium acnes (bacteria related to acne outbreak), both of which play an important role in skin homeostasis and barrier function. Madecassoside significantly inhibited pro-inflammatory cytokine and showed significant effects on improving skin moisturization as well as hyaluronan secretion in human dermal fibroblasts. ²

Another study addressed the effects of Centella asiatica and its active component, asiatic acid, one of the main active constituents directly associated with its wound healing activity. ³ It is reported to exhibit activity in tissue regeneration, cell migration, and the wound repair process by promoting fibroblast proliferation and collagen synthesis.

Additionally, one study mentions that its phytocompounds are considered cosmetically beneficial for their anti-aging role, skin hydration, collagen synthesis, UV protection, and scar healing. ⁴

Researchers conducted a randomized clinical trial on the photoaged skin of 20 female volunteers to study the effects of 5% vitamin C and 0.1% madecassoside (active compound, extracted from Centella asiatica, known to induce collagen expression and/or modulate inflammatory mediators, could thus prevent and correct certain signs of aging) applied topically on the clinical, biophysical and structural properties of the skin. After 6 months of treatment, they observed a significant improvement in the clinical score of wrinkles, suppleness, firmness, roughness and hydration of the skin. Two-thirds of the subjects showed improvement. A network of normally structured elastic fibers was seen to reappear. The results revealed a functional and structural remodeling of the skin that had suffered chronic sun damage. ⁵

Rosehip - Rosa canina

The use of rosehip oil may date back as far as the ancient Egyptians, and it is still used today for its medicinal and cosmetic properties.

An article reviewed by an Indian doctor ⁶ explains that it is commonly used to smooth skin. It is composed, among other things, of rosehips, which are packed with vitamin C, an excellent tool for protecting the skin. Vitamin C acts as an antioxidant. Rosehips help repair skin after sun damage and can even reverse signs of aging caused by too much sun.

It also contains carotenoids, which help keep skin fresh and healthy, and vitamin F, which helps retain moisture in your skin and protect it from damage.

The retinoids in this oil can help brighten your skin, prevent blackheads, and reduce inflammation.

Research shows that rosehip oil helps reduce the appearance of scars. One study of people treated with rosehip oil after skin surgeries found that the treatment helped reduce scar discoloration and lessen the overall appearance of scars. ⁷

Magnolia - Michelia alba

Magnolia is a flowering tree best known for its essential oil, which has long been used as a fragrance ingredient for perfumes and beauty products. It has also been used in traditional medicine in Asia for hundreds of years.

A study ⁸ explains that ultraviolet solar radiation can cause skin photoaging by inducing the secretion of matrix metalloproteinases. It is mentioned that the effects of Michelia alba extract were studied on the expression and activity of matrix metalloproteinases in human skin fibroblast cultures after UVB exposure. The results showed that Michelia alba and its hydrolysates inhibited the activities of collagenase and elastase. In addition, Michelia alba exhibited antioxidant activity, a high content of hyaluronic acid. The results imply that Michelia alba is an effective agent against UVB-induced photodamage. Michelia alba could restore total collagen synthesis reduced by UVB.

Silver fir - Abies alba

Silver fir oil (pectinate) is known for its purifying, tonic, and calming properties. It has antiradicular activity, so it helps protect the skin from free radicals. It gives off an invigorating and fresh scent. ⁹

Frankincense - Boswellia carterii

Frankincense has many benefits, including the ability to strengthen the skin and improve its tone, elasticity, defense mechanisms against bacteria or blemishes, and appearance as someone ages. ¹⁰ Additionally, it is reported to be an effective topical agent for softening facial wrinkles and relaxing the skin. It can help tone and lift the skin, reduce the appearance of scars and acne, and heal wounds. It may also be beneficial for fading stretch marks, surgical scars, or marks associated with pregnancy, and for healing dry or cracked skin. ¹¹ According to a study published in the Journal of Traditional and Complementary Medicine, frankincense oil reduces skin redness and irritation, while producing a more even skin tone. ¹²

Zanthoxylum - Zanthoxylum armatum

A mini-review of recent studies examined essential oils that can be used to increase skin penetration in transdermal applications and the possible mechanisms of their effects. They increase skin penetration by interacting with the stratum corneum. Among them, zanthoxylum is believed to possess this property. ^13,14,15 This oil, with a slightly peppery and refreshing odor, is both calming and tonic.

Rose - Rosa damascena

Its floral, fruity, rosy and tangy fragrance is totally seductive, and without forgetting that its properties are as exceptional as its smell! Soothing, aphrodisiac, healing, firming, regenerating, revitalizing, tonic etc. ¹⁶

In a study conducted on ten essential oils regarding their activities against Propionibacterium acnes and certain cancer cells PC-3, A-549 and MCF-7, it was reported, among others, that rose essential oil showed the best antibacterial activities against P. acnes. ¹⁷

Here is a beauty ritual with Magnolia treatment

References:

1. Bylka W, Znajdek-Awiżeń P, Studzińska-Sroka E, Brzezińska M. Centella asiatica in cosmetology. Postepy Dermatol Alergol. 2013 Feb;30(1):46-9. doi: 10.5114/pdia.2013.33378. Epub 2013 Feb 20. PMID: 24278045; PMCID: PMC3834700.

2. Shen Biosci Biotechnol Biochem. 2019 Mar;83(3):561-568. doi:10.1080/09168451.2018.1547627. Epub 2018 Nov 19. PMID: 30452312.

3. Diniz LRL, Calado LL, Duarte ABS, de Sousa DP. Centella asiatica and Its Metabolite Asiatic Acid: Wound Healing Effects and Therapeutic Potential. Metabolites. 2023 Feb 14;13(2):276. doi:10.3390/metabo13020276. PMID: 36837896; PMCID: PMC9966672.

4. Bandopadhyay S, Mandal S, Ghorai M, Jha NK, Kumar M, Radha, Ghosh A, Proćków J, Pérez de la Lastra JM, Dey A. Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review. J Cell Mol Med. 2023 Mar;27(5):593-608. doi: 10.1111/jcmm.17635. Epub 2023 Feb 8. PMID: 36756687; PMCID: PMC9983323.

5. Haftek M, Mac-Mary S, Le Bitoux MA, Creidi P, Seité S, Rougier A, Humbert P. Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin. Exp Dermatol. 2008 Nov;17(11):946-52. doi: 10.1111/j.1600-0625.2008.00732. x. Epub 2008 May 21. PMID: 18503551.

6. https://www.webmd.com/diet/health-benefits-rosehip-oil Medically Reviewed by Poonam Sachdev on November 23, 2022. Written by WebMD Editorial Contributors.

7. Journal of Cosmetics, Dermatological Sciences and Applications: “Evolution of Post-Surgical Scars Treated with Pure Rosehip Seed Oil.”

8. Chiang HM, Chen HC, Lin TJ, Shih IC, Wen KC. Michelia alba extract attenuates UVB-induced expression of matrix metalloproteinases via MAP kinase pathway in human dermal fibroblasts. Food Chem Toxicol. 2012 Dec;50(12):4260-9. doi: 10.1016/j.fct.2012.08.018. Epub 2012 Aug 17. PMID: 22922035.

9. Yang SA, Jeon SK, Lee EJ, Im NK, Jhee KH, Lee SP, Lee IS. Radical Scavenging Activity of the Essential Oil of Silver Fir (Abies alba). J Clin Biochem Nutr. 2009 May;44(3):253-9. doi: 10.3164/jcbn.08-240. Epub 2009 Apr 25. PMID: 19430614; PMCID: PMC2675024.

10. https://draxe.com/essential-oils/what-is-frankincense/

11. Rafie Hamidpour, Soheila Hamidpour, Mohsen Hamidpour, and Mina Shahlari. Frankincense (乳香 Rǔ Xiāng; Boswellia Species): From the Selection of Traditional Applications to the Novel Phytotherapy for the Prevention and Treatment of Serious Diseases. J Tradit Complement Med. 2013 Oct-Dec; 3(4): 221–226. PMCID: PMC3924999, PMID: 24716181, doi: 10.4103/2225-4110.119723 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924999

12. https://www.doctissimo.fr/sante/aromatherapie/guide-huiles-essentielles/huile-essentielle-d-encens

13. Lan Y, Li H, Chen YY, Zhang YW, Liu N, Zhang Q, Wu Q. Essential oil from Zanthoxylum bungeanum Maxim. and its main components used as transdermal penetration enhancers: a comparative study. J Zhejiang Univ Sci B. 2014 Nov;15(11):940-52. doi:10.1631/jzus. B1400158. PMID: 25367787; PMCID: PMC4228507.

14. Ufuk Koca Caliskan, Methiye Mancak Karakus. Essential oils as skin permeation boosters and their mechanisms of expected effects. University of Gazi, Faculty of Pharmacy, Department of Pharmacognosy and Pharmaceutical Botany 06330 Etiler, Ankara, Turkey. https://www.dermatoljournal.com/articles/essential-oils-as-skin-permeation-boosters-and-their-predicted-effect-mechanisms.html

15. Lan Y, Wu Q, Mao YQ, Wang Q, An J, Chen YY, Wang WP, Zhao BC, Liu N, Zhang YW. Cytotoxicity and enhancement activity of essential oil from Zanthoxylum bungeanum Maxim. as a natural transdermal penetration enhancer. J Zhejiang Univ Sci B. 2014 Feb;15(2):153-64. doi:10.1631/jzus. B1300230. PMID: 24510708; PMCID: PMC3924391.

16. https://www.passeportsante.net/fr/Solutions/HuilesEssentielles/Fiche.aspx?doc=huile-essentielle-rose

17. Yuangang Zu, Huimin Yu, Lu Liang, Yujie Fu, Thomas Efferth, Xia Liu, Nan Wu. Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells. Molecules 2010 Apr 30;15(5):3200-10. doi:10.3390/molecules15053200. PMID: 20657472, PMCID: PMC6263286. https://pubmed.ncbi.nlm.nih.gov/20657472/

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