Inflammation and pain: what natural solutions can help provide relief?

Inflammation et douleur : quelles solutions naturelles peuvent aider à soulager ?

Pain is not always something you simply have to learn to live with.

When it is linked to inflammation, there are natural options that have been studied to help target this inflammatory component and, in some cases, help reduce pain.

Turmeric, boswellia, palmitoylethanolamide (PEA)… behind these names are active ingredients that are currently the subject of significant scientific interest.

It is around several of these active ingredients that we built our Maison Jacynthe Anti-inflammatory Formula, approved by Health Canada to help relieve joint pain and inflammation, as well as joint pain and swelling associated with knee osteoarthritis.

But before talking about the formula, let's understand what happens in our bodies.

Inflammation: enemy or ally?

Inflammation is not inherently bad.

It is a normal response of the body to an injury, such as a wound, infection, or irritation. It plays a role in defense and repair mechanisms.

The problem arises when inflammation becomes persistent or accompanies certain conditions. In a joint, it can contribute to pain, stiffness, and swelling.

This is why targeting the inflammatory component can be part of an approach aimed at regaining greater comfort and mobility.

Why can inflammation cause pain?

During an inflammatory reaction, various chemical mediators are released into the tissues. Some can sensitize the nerve endings that transmit pain signals.

In other words, inflammation and pain can fuel each other, even though not all pain is necessarily inflammatory.

This is an important distinction: persistent pain can have many causes, and new, intense, or unexplained pain deserves a professional evaluation.

The natural active ingredients at the heart of our formula

1. Boswellia serrata: one of the major plant-based active ingredients studied for joint health

Each capsule provides:

333 mg of Boswellia serrata standardized to 40% boswellic acids.

Boswellia, also known as Indian olibanum, is a resin that has been traditionally used for centuries. Today, its boswellic acids are of particular interest to researchers.

Clinical trials and meta-analyses have studied various extracts of Boswellia serrata for osteoarthritis and report improvements in parameters such as pain, stiffness, and joint function. However, it should be kept in mind that the extracts and doses vary from one study to another. 

It is therefore much more than a "trendy" plant: boswellia now has clinical literature on its use in osteoarthritis.

2. Turmeric: the classic, but standardized

Our formula provides per capsule:

100 mg of Curcuma longa extract, equivalent to 400 mg of dried turmeric, standardized to 35% curcuminoids.

This standardization is interesting because it is not simply a matter of milligrams of turmeric powder: curcuminoids make up one of the most studied families of bioactive compounds in turmeric.

A meta-analysis of meta-analyses published in 2024, combining 11 meta-analyses of randomized trials, reports statistically significant improvements in several measures of pain, function, and stiffness in people with osteoarthritis. 

Another systematic review and meta-analysis involving 10 randomized trials and 786 participants with knee osteoarthritis also observed an improvement in pain compared to the placebo. Turmeric was notably as effective as standard pain medications.

This is why turmeric has a place in a formula designed for joint comfort.

3. PEA: the lesser-known ingredient that deserves our attention 

Each capsule contains:

100 mg of palmitoylethanolamide, or PEA.

PEA is a lipid naturally present in the body and studied for its role in modulating mechanisms associated with inflammation and pain.

And here, the literature is particularly interesting.

A systematic review and meta-analysis from 2023 included 11 double-blind randomized trials representing 774 participants. The pooled analysis showed a reduction in chronic pain scores in favor of PEA. The authors also report improvements in function and quality of life in several studies, while emphasizing that the optimal indications and doses still need to be better established. 

A more recent meta-analysis involving 18 studies and 1,196 participants also reports a reduction in pain, particularly at 6 and 8 weeks, as well as favorable results in different types of pain. 

Another review, however, highlights significant heterogeneity between some studies and the need for additional high-quality clinical trials. 

4. Piperine: why combine black pepper with turmeric?

The formula also provides:

4 mg of piperine from Piper nigrum.

Piperine complements the combination with turmeric, a combination that has been the subject of studies on the bioavailability of curcuminoids.

In other words, piperine allows the body to better absorb the active components of turmeric. It is scientifically more robust.

5. L-lysine

Each capsule also provides 45 mg of L-lysine.

Lysine is an essential amino acid, meaning that our body cannot produce it and must obtain it from food.

It generally participates in protein synthesis and particularly helps in the formation of collagen. 

One formula, several complementary approaches

Our formula does not rely on a single ingredient.

It brings together:

  • Boswellia serrata, standardized in boswellic acids
  • Curcuma longa, standardized in curcuminoids
  • PEA, studied in the context of different types of pain
  • piperine, combined with turmeric
  • L-lysine

The recognized benefits of our Anti-inflammatory Formula

✓ Helps relieve joint pain and inflammation.

✓ Helps relieve joint pain and swelling associated with knee osteoarthritis.

✓ Helps with collagen formation.

Is it only for osteoarthritis?

No. The indication regarding knee osteoarthritis is very specific, but the product also has the more general claim:

Helps relieve joint pain and inflammation.

So for anyone looking for a natural approach to thecomfort of their joints.

Not all pain is inflammatory

Back pain, muscle pain, nerve pain, injury, osteoarthritis, inflammatory disease: the word "pain" covers very different realities.

A natural formula therefore does not replace the search for the cause when pain persists, worsens, occurs suddenly, or is accompanied by other symptoms.

Can we act in other ways than with a supplement?

Absolutely.

An approach to joint comfort can also include adapted movement, maintaining muscle strength, sleep, a varied diet, and addressing any medical factors.

The supplement then becomes one tool among others.

The question many people ask

"Can a natural anti-inflammatory really relieve pain?"

Some natural active ingredients have been the subject of clinical trials showing effects on certain types of pain, particularly in the context of joint health and osteoarthritis.

This does not mean that they work for all types of pain, or that everyone will get the same result.

In our formula, boswellia, turmeric, and PEA each have their own clinical literature, while the finished product has its own approved claims regarding joint pain and inflammation.

Maison Jacynthe Anti-inflammatory Formula

A synergy designed for joint comfort.

Boswellia serrata + turmeric + PEA + lysine + piperine.

A formula that helps relieve joint pain and inflammation, as well as joint pain and swelling associated with knee osteoarthritis.

Who might it be particularly suitable for?

The person who says:

"My joints hurt."
"I am stiff."
"My knee is painful or swollen due to my osteoarthritis."
"I am looking for a natural option to support my joint comfort."

Key studies

The 2024 meta-analysis on turmeric and osteoarthritis: PubMed – Curcumin and osteoarthritis⁠

The review and meta-analysis on Curcuma longa and knee osteoarthritis: Study – Curcuma longa and knee pain⁠

The 2024 systematic review on Boswellia serrata and osteoarthritis: Study – Boswellia serrata and osteoarthritis⁠

The 2023 meta-analysis on PEA and chronic pain: PubMed – PEA and chronic pain⁠

The more recent meta-analysis involving 18 studies and 1,196 participants: PubMed – PEA and pain management⁠