Four medicinal plants combined in a botanical formula
Phytotherapy offers us an extraordinary world of plant molecules.
Some plants have been traditionally used for centuries to support periods of nervousness and difficulty falling asleep.
Maison Jacynthe's Calmant formula combines four concentrated plant extracts.
Scutellaria: a plant traditionally associated with relaxation
Scutellaria lateriflora
American skullcap is traditionally used in phytotherapy to relieve nervousness and restlessness.
It notably contains flavonoids, including baicalin and scutellarin.
These compounds have attracted researchers' interest due to their potential interactions with certain neurological mechanisms, particularly those associated with GABAergic neurotransmission.
However, human clinical data remain preliminary.
In Calmant: 300 mg of 10:1 extract, equivalent to 3,000 mg of dried plant.
Passionflower: a traditional ally for restless minds
Passiflora incarnata
With its spectacular flowers, passionflower is one of the best-known plants in traditional phytotherapy for nervousness.
It notably contains flavonoids such as vitexin and isovitexin.
Several studies have examined its potential influence on anxiety and relaxation. Some suggest encouraging results, but human studies are still limited.
Passionflower is particularly interesting in an approach aimed at supporting periods of mental restlessness.
In Calmant: 250 mg of 4:1 extract, equivalent to 1,000 mg of dried plant.
Valerian: a long history with sleep
Valeriana officinalis
Used since antiquity, valerian remains one of the most studied medicinal plants in the field of sleep.
Its root notably contains valepotriates and valerenic acids, compounds that interest scientists for their activity on certain enzymes and receptors of the nervous system, particularly in connection with GABA.
A systematic review and meta-analysis published in 2020 analyzed 60 studies involving 6,894 participants.
Researchers noted variable results, particularly depending on the nature and quality of the preparations used.
Valerian thus retains an important place in the phytotherapeutic tradition, even if its effectiveness against chronic insomnia is not established by contemporary clinical studies, with their acknowledged limitations, particularly regarding complex phytotherapeutic products.
In Calmant: 150 mg of 4:1 extract, equivalent to 600 mg of dried root.
Lemon balm: aromatic sweetness at the service of calm
Melissa officinalis
This plant from the mint family has long been appreciated for its lemon scent and its traditional uses related to relaxation.
Lemon balm notably contains rosmarinic acid, a phenolic compound studied for various biological activities.
Preclinical studies suggest that some of its constituents could influence mechanisms related to GABA.
Human studies have also explored its potential for stress and sleep, with encouraging results, but still insufficient to establish effectiveness according to contemporary scientific criteria.
In Calmant: 150 mg of 4:1 extract, equivalent to 600 mg of dried plant.
Why combine these four plants?
The richness of the formula lies in the diversity of its plant constituents.
Each plant brings its own set of natural compounds.
Some are studied for their potential interactions with GABAergic mechanisms, others for their traditional uses during periods of nervous tension or difficulty falling asleep.
Their combination allows several traditional phytotherapeutic uses to be brought together in a single formula.
However, it remains important to distinguish the scientific potential of each plant from the clinical effectiveness of their precise combination, which would require studies on the complete formula.
What scientific studies say
Research is encouraging for certain plants
Valerian: a 2020 review of 60 studies and 6,894 participants examined its usefulness for sleep and anxiety. Results vary depending on the preparations.
Passionflower: a few studies suggest potential for reducing anxiety, but trials remain limited.
Botanical combinations: a 2025 review of 51 randomized trials notes promising results for certain combinations containing valerian and passionflower, without definitive conclusions.
Scientific references
Valerian — Systematic review and meta-analysis (2020), 60 studies and 6,894 participants
https://pmc.ncbi.nlm.nih.gov/articles/PMC7585905/
Passionflower — Randomized clinical study (2024), 65 participants
https://pubmed.ncbi.nlm.nih.gov/38646244/
Over-the-counter products and botanical combinations — Review of 51 randomized trials (2025)
