“Thank you for your presentation with Maison Jacynthe regarding your products and information. Super interesting. My partner is a type 1 diabetic. We started the products and had to further reduce the insulin dose. I am a certified diabetes educator and I am really impressed with your products. I am a nurse by training. Thank you and have a nice day.” - Sophie S.
Here are Gluconig & Metzaben, two formulas for metabolism and glucose explained by their designer Pierre Haddad, researcher and scientific director.
To learn more about Pierre, the formulator of these two products and his live presentation, click here !
Combination of seaweed and black seed blend to support muscles, liver and pancreas.
To help reduce the glucose spike after a meal and maintain healthy blood levels and it can be used even if you do not have conditions, it cannot unbalance the system in a normal individual, but can mitigate the effect of fast sugars so not bad for a healthy individual.
Can a diabetic take it? It doesn't replace medication; rather, it helps reduce the sugar rush when eating and slows down fat absorption. Black seed helps the body better manage sugar.
Formula developed over the years with this understanding of metabolic diseases to act on multiple levels. Group of natural compounds to manage glucose.
Contains plants for blood glucose:
Natural Ginseng: Can help manage blood glucose in different metabolic conditions.
Chromium: Essential mineral element; for many enzymes related to nutrient management and insulin response. Studies show it helps maintain healthy levels.
Also contains plants that act on inflammation: turmeric is one of the most recognized anti-inflammatory plants but also acts on the liver in combination with milk thistle. It manages stress due to inflammation.
Vitamin D: Vitamin D deficiency = higher risk of metabolic disease.
Vitamin E: Oil-soluble antioxidant aspect will protect against oxidative stress in membranes that contain glucose transporters and enzymes. Helps break the cycle of toxic lipid generation in the liver.
Jean-Yves Dionne's take on the ingredients in these two products
Combination of the 2 algae (Ascophyllum nodosum / Fucus vesiculosus): Super interesting, this will reduce the absorption of sugar, reduce blood sugar levels especially after meals (the sugar peak after meals, not so much the one on an empty stomach).
Nigella : a fascinating plant that helps sugar metabolism, helps normalize several phenomena (there are studies on the cardiovascular level), it acts where other things do not.
Combined with the first ingredient which is the combination of 2 algae to reduce sugar absorption and nigella which will improve back management, it does not say that it will cure anyone, but it will certainly be a tool for managing sugar metabolism.
It's not for everyone. It's a therapeutic tool specific to sugar management.
3 types of people:
- For someone who comes to be told "Be careful, diabetes is coming tomorrow morning!" (But who is not yet on medication). That's the typical client.
- Someone who has an increasing waistline that never wants to go away (it's called metabolic syndrome) and the diet hasn't changed, but in the meantime this can be helpful.
- And under medical supervision or by a professional like him , for diabetics, we can manage medications by including this. Only under the advice of a professional . You should not do this alone when taking medication. Because beyond medications as such, natural health products, the biggest problem we have is when we mix this with a medication or medications.
Milk thistle : A plant that works on the liver. According to a paper by a researcher in Italy, it is used for liver cirrhosis, metabolic syndrome, fatty liver, and solvent poisoning. A plant that supports and regenerates the liver and increases the production of antioxidant factors such as glutathione peroxidase. This product has no significant digestive effects.
Ginseng Extract : Research shows that ginseng (ginsenosides/standardized extract) will have an impact in helping the liver detoxify alcohol the day after the night before. According to Chinese medicine, ginseng increases vital energy, it is an adaptogen that increases the ability to adapt to stress. Metabolic disturbances are often the result of stress, whether due to environmental toxicity or stress that we experience every day. There is therefore a logical complementarity.
Nigella : as mentioned in the other product, it is a fascinating plant that will help sugar metabolism, help normalize several phenomena (there are studies at the cardiovascular level), it acts where other things do not.
Chromium : It works to normalize, to work on diabetes, on weight loss, only if you're deficient in it. Why? Because if you don't have chromium, insulin will be less effective. In the notion of metabolism, having a little chromium to ensure that you don't have a deficiency. The primary cause of chromium deficiency is sugar consumption.
Turmeric : it is in its traditional indication here (not in its anti-inflammatory indication), it is really in the Ayurvedic understanding, a liver tonic.
This product is more general (unlike the other (Gluconig) which is aimed at specific conditions). We could do cures of this; let's think again about the notion of Chinese medicine, or the change of seasons (because it is a particular stress for the body and we must adapt). It supports the metabolism, especially the liver. A great idea in complementarity (unless you are taking medication, only under the advice of a professional). This product is more general; at the same time, you have digestive pains, returns from vacation that you did not pay attention to, during and after the holidays, it is time to take it. It is more of a product that will help support the functions of detox, improvement of metabolism, a complement to the diet, phase change, yes absolutely correct, no problem.
Pierre Haddad answers your questions
Nathalie B.: I have a fatty liver, is that what my ultrasound report shows? I imagine that could help?
Indeed, milk thistle derivatives (especially silymarin contained in Metabzen) have protective effects on the liver in fatty liver conditions (steatosis and non-alcoholic steatohepatitis). Our own animal studies have shown significant beneficial effects. In humans, however, the results were more mixed with few effects superior to placebo for the severity of the disease but significant effects on certain parameters were observed; for example, on liver enzymes present in the blood.
Carolyne D.: If you are not diabetic but are close to fifty and you want to avoid type 2 diabetes, which of the two is best to take? Thank you.
The products are designed to help better manage metabolism in general and blood glucose in particular. This can theoretically help prevent metabolic diseases. Several of the products' components also have clinical evidence of benefits for people with diabetes. Metabzen is the one designed to better manage several body systems involved in metabolic disorders and would be the most suitable product, depending on your question.
Sylvie R.: Interaction with cortisone and soon hydroxychloroquine?
Glucocorticoids like cortisone have the effect of increasing blood glucose. Therefore, the products may be less effective. For hydroxychloroquine, I will need to do more research.
Lise D.: Is there calcium in these products because I am not allowed to take calcium?
No, there is no appreciable amount of calcium in the products.
Josée-Anne B.: If we have good general health and a good lifestyle, which of the two would be recommended?
Metabzen is more general and probably better suited to your situation while Gluconig helps more to reduce the impact of food on blood glucose after a meal.
Lise D.: Is there one of the two that would help with cholesterol?
No, there is no ingredient that specifically targets cholesterol.
Christine L.: Can we take these two products if we take collagen?
Yes, no contraindications.
Sonya B.: Can we take Gluconig and St. John's Wort?
St. John's wort should not affect the action of brown seaweed, since the latter acts on digestive enzymes in the intestines, while St. John's wort acts on enzymes in the intestinal wall and liver. St. John's wort could theoretically affect the effect of black seed, but there is not enough scientific data to make an informed opinion.
Marie C.: Can people who don't have diabetes take it? And I also drink 1 to 2 glasses of wine a day, could that have an impact?
The products are indicated for the prevention of metabolic disorders and not specifically for the treatment of diabetes, so yes, you can take them to help maintain a healthy metabolism. The moderate alcohol consumption you describe should not have an impact.
Bernadette S.: Is it OK to take blood thinners or anti-hormone treatment for breast cancer?
It is advisable to discuss the use of these products with your doctor(s). You should always be very careful when taking blood thinners, especially those like warfarin, which have a narrow therapeutic window.
Micheline G.: The role of chrome please
Chromium (III) is a micronutrient that plays an important role in glucose metabolism. In particular, it reduces blood glucose and glycated hemoglobin (HbA1C) in diabetics without affecting that of normal individuals 1 . These effects increase with the level of insulin resistance 2 ; this is consistent with its role in facilitating the action of insulin at its receptors on the body's cells. Health Canada recognizes chromium for its ability to help the body metabolize carbohydrates and lipids 3 . Its mode of action is therefore complementary to that of American ginseng.
- Balk EM, Tatsioni A, et al. (2007). Effect of chromium supplementation on glucose metabolism and lipids: a systematic review of randomized controlled trials. Diabetes Care. 30(8):2154-63.
- Cefalu WT, Rood J, et al. (2010). Characterization of the metabolic and physiologic response to chromium supplementation in subjects with type 2 diabetes mellitus. Metabolism. 59(5):755-62.
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Chromium monograph: https://webprod.hc-sc.gc.ca/nhpid-bdipsn/monoReq.do?id=65
Nathalie D.: So if we are already taking metformin then we should not take these?
Metformin is an oral hypoglycemic drug that helps lower blood glucose by acting primarily on the liver and skeletal muscle. In theory, therefore, the effects of the drugs could be additive to those of metformin, and this has the potential to cause hypoglycemia if the additive effects are too strong. It is advisable to discuss the combined use of metformin and the drugs with your doctor. It is entirely possible to manage the combination by adjusting the doses of either the drug or the drugs.
Diane M.: Is it harmful if we no longer have a gallbladder?
The turmeric in Metabzen is known to increase bile secretion. However, in theory, there should be no serious consequences of a missing gallbladder. However, it's best to discuss this with your doctor before starting to consume the product.
Johanne P.: Is it good for a tendency to high blood pressure?
The products do not contain any ingredients specifically indicated to help lower blood pressure. On the contrary, the American ginseng present in Metabzen is said to increase blood pressure. For the Gluconig product, there is also a warning if you suffer from hypertension or are taking antihypertensive medications.
Marie Eve: Is Gluconig compatible with insulin, metformin, diabetes?
Metformin is an oral hypoglycemic drug that helps lower blood glucose by acting primarily on the liver and skeletal muscle. Insulin, on the other hand, acts at multiple levels to also lower blood glucose. In theory, therefore, the effects of the products could be additive to those of metformin and/or insulin. This has the potential to cause hypoglycemia if the additive effects are too strong. It is advisable to discuss the combined use of metformin, insulin, and the products with your doctor. It is entirely possible to manage the combination by adjusting the doses of either the drug or the products.
Marie Pierre: To take for life or in cycles?
It is possible to take the products for long periods of time, but it is also good to take breaks from consumption periodically; for example, stop taking them for 2-3 weeks every 6 months or one month per year.
Hélène B.: Are these formulas to be taken 12 months a year or just as a course of treatment?
It is possible to take the products for long periods of time, but it is also good to take breaks from consumption periodically; for example, stop taking them for 2-3 weeks every 6 months or one month per year.
Sylvie C.: Which one is better for waist size?
None of the products are designed specifically to reduce body weight or waist circumference.
Antoinette S.: When taking blood pressure pills, can we take them?
It depends on the type of medication you're taking. The American ginseng in Metabzen tends to increase blood pressure. Gluconig also has a warning if you have high blood pressure or are taking antihypertensive medication. It's best to discuss this with your doctor.
Marie Eve: Is Gluconig also good for regulating bad cholesterol?
No, there is no ingredient that specifically targets cholesterol.
Carolyne D.: Can we take it while we are growing at 12 years old?
Both products are recommended for use in adults as data in children for the majority of ingredients is lacking.
Lise D.: Can it lower glucose and cause hypoglycemia?
Both products can effectively help maintain normal blood glucose levels. There is a risk of hypoglycemia, but this is especially true if the products are combined with medications that lower blood glucose (oral hypoglycemics or insulin).
Danielle F.: Even with taking Syntroid?
Syntroid is a thyroid hormone supplement used to treat people whose thyroid gland does not produce enough hormones. Thyroid hormones affect the metabolism of proteins, sugars, and fats. Therefore, there may be a potential interaction between the products and Syntroid in terms of pharmacological action. You should consult your doctor to discuss the combined use of the products with this medication before starting them.
Marie Pierre: Can we take the treatment (metformin and Ozempic) plus your product?
It is possible to combine the products with medications such as metformin and Ozempic, but you should inform your doctor and monitor your blood sugar closely because there may be additive or synergistic effects that can cause hypoglycemia.
Nathalie B.: Is this a preventative product or is it exclusive to diabetics?
The products are designed to help better manage metabolism in general and blood glucose in particular. This can theoretically help prevent metabolic diseases. Several of the products' components also have clinical evidence of benefit in people with diabetes, but should be taken in close consultation with your doctor, especially if the person is taking medication.
Nicole C.: Do we see the effects of the benefits of these products on the body fairly quickly?
It depends on what you consider fast… but generally, no. It can take several weeks for significant benefits to develop. Most clinical studies supporting the actions of individual product components have spanned several weeks or even months.
Diane G.: Does one of the two products put you back into ketosis?
No, none of the products are designed to promote ketosis.
Josée-Anne B.: If we have good general health and a good lifestyle, which of the two would be recommended?
Metabzen is more general and probably better suited to your situation while Gluconig helps more to reduce the impact of food on blood glucose after a meal.
Micheline B.: Do these products protect the bladder when there are frequent urinary tract infections?
No, the products do not contain any ingredients specifically targeting frequent urinary tract infections. I'm sure you already know that cranberry products are well-suited for this situation.
Marie Pierre: Mr. Haddad, can we combine allopathic treatment with your Gluconig?
Yes, it is possible to combine Gluconig with allopathic medications. However, there is a possibility of pharmacological interaction, so it is advisable to discuss their combined use with your doctor before starting to take them.
Lise D.: How quickly can you see a difference if you are diabetic?
It can take several weeks for the benefits of products to be significantly felt. Most clinical studies supporting the actions of various product components have spanned several weeks or even months.
Lucie L.: Good for fatty liver and insulin resistance?
Metabzen contains several components that have protective effects on the liver (turmeric and milk thistle) and help improve insulin activity (American ginseng, black cumin and chromium). In particular, milk thistle derivatives (especially silymarin contained in Metabzen) have protective effects on the liver in fatty liver conditions (steatosis and non-alcoholic steatohepatitis).
Cyndie B.: Can it be used for children with type 1 diabetes?
Both products are recommended for use in adults as data in children for the majority of ingredients is lacking.
Johanne P.: Can we use it if we already have insulin?
Yes, but you should discuss this with your doctor before starting to use these products, as they may have similar actions to those of insulin or increase its action. Therefore, there is a risk of hypoglycemia if additive or synergistic effects occur.
Sylvie R.: With 2 autoimmune diseases, like Hashimoto's thyroiditis and polymyalgia heumatica, cortisone can induce my fatty liver and I'm not done with cortisone after 6 years! Aside from cutting out fructose, doing a little exercise, I wonder if it's worth the cost to spend on supplements that have more or less helped me all these years?
Metabzen contains several components that have protective effects on the liver (turmeric and milk thistle) and help improve insulin activity (American ginseng, black cumin and chromium). In particular, milk thistle derivatives (especially silymarin contained in Metabzen) have protective effects on the liver in fatty liver conditions (steatosis and non-alcoholic steatohepatitis).
Lise B.: Can we hope to have it in powder form? Possibly
To my knowledge, there are no plans to produce powdered preparations of either product. It is notably more difficult to dose the powdered product correctly, and Health Canada requires that natural health products with an NPN (Natural Product Number, therefore authorized to be marketed) be in a specific dosage form. The capsules therefore contain the correct amount of powder. You can always open the capsules and pour their contents into a glass of water or juice if you prefer not to consume the capsules themselves.
Hélène B.: What does he think of the ketogenic lifestyle with carbohydrate control?
The "ketogenic" lifestyle requires strict eating habits that can be difficult to implement. However, there are numerous studies demonstrating the benefits of such a ketogenic diet on carbohydrate control, particularly in the context of metabolic diseases such as type 2 diabetes.
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