Health Support

Used in herbal medicine as a hepatoprotective/liver-protective agent, as an adaptogen to help increase energy and stress resistance (in cases of mental or physical fatigue due to stress), to support the immune system. Source of fungal polysaccharides with immunomodulatory properties. Promotes wound healing. Helps to improve cognitive function and memory in adults, to contribute to the maintenance of peripheral circulation, the development and maintenance of bones/cartilage/teeth/(and) gums, energy metabolism/(and) tissue formation, red blood cells, collagen, connective tissue formation and repair, to maintain/support healthy skin/hair/nails, normal iron transport in the body, the body's ability to metabolize nutrients, immune functions/the immune system, to help stimulate the secretion of bile by the liver (choleretic) and stimulate contraction of the gallbladder (cholagogue), to aid digestion, as a liver tonic, to help relieve flatulent dyspepsia (carminative). Source of (an) antioxidant(s) for the maintenance of good health, which helps fight/protect (cells) against/reduce free radicals. Milk thistle is used as a hepatoprotective/liver-protective agent, and Curcuma longa as an anti-inflammatory to help relieve joint pain. Helps prevent vitamin D deficiency and may reduce the risk of developing osteoporosis in individuals with vitamin D deficiency.

Among its ingredients, we find:

Japanese knotweed

In this plant, more than 110 compounds have been isolated and identified, in which anthraquinones, stilbenes (including resveratrol which is part of it and known for its beneficial effects, such as anticarcinogenic and antioxidant) and flavonoids would be the main bioactive ingredients for their pharmacological properties, such as improvement of microcirculation, protective effects of the myocardium, endocrine regulation, anti-arteriosclerotic activity, antioxidant activity, antitumor activity, antiviral activity and treatment of skin inflammation, burns and scalds. ¹

1. Liu S, Zhang R, Zhang X, Zhu S, Liu S, Yang J, Li Z, Gao T, Liu F, Hu H. The Invasive Species Reynoutria japonica Houtt. as a Promising Natural Agent for Cardiovascular and Digestive System Illness. Front Pharmacol. 2022 Jun 13; 13:863707. doi: 10.3389/fphar.2022.863707. PMID: 35770098; PMCID: PMC9234309.

N-Acetyl-L-cysteine

Antioxidant, precursor of protein synthesis and glutathione production ^1,2 and Neuroprotector3

^{1. Sahasrabudhe SA, Terluk MR, Kartha RV. N-acetylcysteine ​​Pharmacology and Applications in Rare Diseases-Repurposing an Old Antioxidant. Antioxidants (Basel). 2023 Jun 21;12(7):1316. doi:10.3390/antiox12071316. PMID: 37507857; PMCID: PMC10376274.}

^{2. Yin J, Ren W, Yang G, Duan J, Huang X, Fang R, Li C, Li T, Yin Y, Hou Y, Kim SW, Wu G. L-Cysteine ​​metabolism and its nutritional implications. Mol Nutr Food Res. 2016 Jan;60(1):134-46. doi: 10.1002/mnfr.201500031. Epub 2015 Jun 12. PMID: 25929483.}

^{3. Alkandari AF, Madhyastha S, Rao MS. N-Acetylcysteine ​​Amide against Aβ-Induced Alzheimer's-like Pathology in Rats. Int J Mol Sci. 2023 Aug 12;24(16):12733. doi:10.3390/ijms241612733. PMID: 37628913; PMCID: PMC10454451.}

Ginkgo biloba

Ginkgo biloba is known to help improve cognitive function and memory. It helps maintain peripheral circulation by increasing blood flow to the brain. ¹ Ginkgo may be a natural aphrodisiac by relaxing blood vessels and increasing blood flow.

The results of another study support the positive effect of Ginkgo biloba on the sexual function of postmenopausal women. It was conducted on 2 groups of 40 participants; one group received 120 to 240 mg of Ginkgo biloba daily, and the other took a placebo, for 30 days. Most areas of sexual function including sexual desire, sexual pleasure, orgasm, importance of sex in the last month and importance of sex compared to previous years were significantly improved in the group taking Ginkgo biloba. The mean score of total sexual function in the group taking Ginkgo biloba showed a significant difference from that of the placebo group (P < 0.05). ²

1. Valikovics A., 2007. Investigation of the effect of vinpocetine on cerebral blood flow and cognitive functions. Ideggyogy Sz, 60(7-8): 301-310
Patyar S. et al., 2011. Role of vinpocetine in cerebrovascular diseases. Pharmacol Rep, 63(3): 618-628

2. S. Taavoni, M. Amiri, H. Haghani, N. SeiedFatemi, EPA-0145 – Menopausal women's sexual function and use of ginkgo biloba: a randomized placebo-controlled trial, European Psychiatry, Volume 29, Supplement 1, 2014, Page 1, ISSN 0924-9338, https://doi.org/10.1016/S0924-9338(14)77617-5.

Zinc

Deficiencies in this essential mineral can lead to a decrease in libido. A 2021 randomized controlled trial examined the effect of zinc on testosterone levels and sexual function in postmenopausal women whose serum zinc levels were below 62 mcg/dL. Researchers found that zinc supplementation in the intervention group significantly improved sexual desire, arousal, orgasm, satisfaction, vaginal wetness, pain during intercourse, and overall sexual function compared to the control group. ¹

1. Mazaheri Nia L, Iravani M, Abedi P, Cheraghian B. Effect of Zinc on Testosterone Levels and Sexual Function of Postmenopausal Women: A Randomized Controlled Trial. J Sex Marital Ther. 2021;47(8):804-813. doi: 10.1080/0092623X.2021.1957732. Epub 2021 Jul 27. PMID: 34311679.

Vitamin A

This vitamin is necessary for maintaining good vision and a healthy immune system, and is also essential for growth and development.1

^{1. William S. Blaner, Chapter 5 - Vitamin A and provitamin A carotenoids, Editor(s): Bernadette P. Marriott, Diane F. Birt, Virginia A. Stallings, Allison A. Yates, Present Knowledge in Nutrition (Eleventh Edition), Academic Press, 2020, Pages 73-91, ISBN 9780323661621, https://doi.org/10.1016/B978-0-323-66162-1.00005-6.}

Nigella

Nigella sativa is also known as black cumin. The flowers of the plant produce small fruits from which small black seeds emerge, which are then cold-pressed to obtain this essential oil. This medicinal plant is rich in history; its virtues were already praised in the time of the Egyptian pharaohs. It has been traditionally and clinically used in the treatment of several diseases for a very long time in Arab countries and is also very popular in Ayurvedic medicine. It has a wide range of activities and many properties that scientists are discovering over the years.

Several published studies have revealed its activities, including the following: ¹

Anti-inflammatory, antibacterial, antifungal, anthelmintic, antioxidant, antiproliferative, proapoptotic, antiepileptic, improvement of artherogenesis, antidiabetic, antitumor, antimicrobial, lipid profile dysfunction.

1. Zahra Gholamnezhad, Shahrzad Havakhah, Mohammad Hossein Boskabady. Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: A review Elsevier, Journal of Ethnopharmacology Volume 190, 22 August 2016, Pages 372-386. https://www.sciencedirect.com/science/article/abs/pii/S0378874116304214

Copper

Copper is needed to help your body use iron. It is also important for nerve function, bone growth, and to help your body use sugar. ¹

1. https://www.mayoclinic.org/drugs-supplements/copper-supplement-oral-route-parenteral-route/description/drg-20070120

Vitamin C

It helps prevent vitamin C deficiency, maintain the body's ability to metabolize nutrients, the development and maintenance of bones, cartilage, teeth and/or gums and connective tissue formation, and the maintenance/support of immune system functions. Promotes wound healing and collagen formation. It is a source of antioxidants for the maintenance of good health.

Turmeric

It is anti-inflammatory to reduce joint pain ¹ , aids digestion, helps with proper bile secretion ^2,3 , helps maintain healthy blood sugar levels ⁴ and has anti-carcinogenic properties. ^5,6

^{1. Kocaadam B, Şanlier N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health. Crit Rev Food Sci Nutr. 2017 Sep 2;57(13):2889-2895. doi:10.1080/10408398.2015.1077195. PMID: 26528921.}

^{2. Mills, S., Bone, K. The Essential Guide to Herbal Safety. St. Louis (MO): Elsevier Churchill Livingstone. 2005.}

^{3. Blumenthal, M. et al. Herbal Medicine: Expanded Commission E Monographs. Boston (MA): Integrative Medicine Communications; 2000.}

^{4. Dehzad MJ, Ghalandari H, Nouri M, Askarpour M. Effects of curcumin/turmeric supplementation on glycemic indices in adults: A grade-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Diabetes Metab Syndr. 2023 Sep 19;17(10):102855. doi: 10.1016/j.dsx.2023.102855. Epub ahead of print. PMID: 37748368.}

^{5. Dorai T, Gehani N, Katz A. Therapeutic potential of curcumin in human prostate cancer-I. curcumin induces apoptosis in both androgen-dependent and androgen-independent prostate cancer cells. Prostate Cancer Prostatic Dis. 2000 Aug;3(2):84-93. doi: 10.1038/sj.pcan.4500399. PMID: 12497104.}

^{6. Jiang AJ, Jiang G, Li LT, Zheng JN. Curcumin induces apoptosis through mitochondrial pathway and caspase activation in human melanoma cells. Mol Biol Rep. 2015 Jan;42(1):267-75. doi:10.1007/s11033-014-3769-2. Epub 2014 Sep 28. PMID: 25262359.}

Milk thistle

It helps support liver/hepatic functions ¹ and has hepatoprotective properties. ^2,3

1. Gillessen A, Schmidt HH. Silymarin as supportive treatment in liver diseases: A narrative review. Adv Ther. 2020 Apr;37(4):1279-1301. doi:10.1007/s12325-020-01251-y. Epub 2020 Feb 17. PMID: 32065376

2. Abenavoli, L. et al. Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases. Phytother. Res. 2018; 32:2202-2213.

3. Mengs U, Pohl RT, Mitchell T. Legalon® SIL: the antidote of choice in patients with acute hepatotoxicity from amatoxin poisoning. Curr Pharm Biotechnol. 2012 Aug;13(10):1964-70. doi:10.2174/138920112802273353. PMID: 22352731; PMCID: PMC3414726

Hydrolyzed collagen

Ingesting hydrolyzed collagen for 90 days is effective in reducing skin aging, as it reduces wrinkles and improves skin elasticity and hydration. ^1,2

1.by Miranda RB, Weimer P, Rossi RC. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. Int J Dermatol. 2021 Dec;60(12):1449-1461. doi: 10.1111/ijd.15518. Epub 2021 Mar 20. PMID: 33742704.

2.vans M, Lewis ED, Zakaria N, Pelipyagina T, Guthrie N. A randomized, triple-blind, placebo-controlled, parallel study to evaluate the efficacy of a freshwater marine collagen on skin wrinkles and elasticity. J Cosmet Dermatol. 2021 Mar;20(3):825-834. doi: 10.1111/jocd.13676. Epub 2020 Sep 15. PMID: 32799362; PMCID: PMC8176521.

Vitamin D

Vitamin D allows for better absorption of calcium in the body and contributes to the maintenance and healthy formation of bones and teeth. ^1,2

1. Institute of Medicine (US) Committee to Review Dietary Reference Intakes for Vitamin D and Calcium; Ross AC, Taylor CL, Yaktine AL, et al., editors. Dietary Reference Intakes for Calcium and Vitamin D. Washington (DC): National Academies Press (US); 2011. Available from: https://www.ncbi.nlm.nih.gov/books/NBK56070/ doi: 10.17226/13050

2. Heaney RP. Vitamin D in health and disease. Clin J Am Soc Nephrol. 2008 Sep;3(5):1535-41. doi: 10.2215/CJN.01160308. Epub 2008 Jun 4. PMID: 18525006; PMCID: PMC4571146.

Reishi

Reishi is one of the oldest medicinal mushrooms used in Asian regions and is therefore one of the most studied to date. It is widely used for the general promotion of health and longevity. Among its many bioactive compounds are polysaccharides, triterpenes, ganoderic acids, phenols, amino acids, lignin, vitamins, nucleosides, nucleotides, sterols, steroids, proteins and unsaturated fatty acids, and inorganic ions. ¹

Reishi has many activities, such as: ^2,3,4,5

Anticancer, immunomodulatory, antitumor, hepatoprotective, antiviral.

1. Venturella G, Ferraro V, Cirlincione F, Gargano ML. Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials. Int J Mol Sci. 2021 Jan 10;22(2):634. doi:10.3390/ijms22020634. PMID: 33435246; PMCID: PMC7826851.

2. Sliva D. Ganoderma lucidum (Reishi) in cancer treatment. Integra Cancer Ther. 2003 Dec;2(4):358-64. doi:10.1177/1534735403259066. PMID: 14713328.

3. Lin ZB, Zhang HN. Anti-tumor and immunoregulatory activities of Ganoderma lucidum and its possible mechanisms. Acta Pharmacol Sin. 2004 Nov;25(11):1387-95. PMID: 15525457.

4. Ahmad MF, Ahmad FA, Zeyaullah M, Alsayegh AA, Mahmood SE, AlShahrani AM, Khan MS, Shama E, Hamouda A, Elbendary EY, Attia KAHA. Ganoderma lucidum: Novel Insight into Hepatoprotective Potential with Mechanisms of Action. Nutrients. 2023 Apr 13;15(8):1874. doi:10.3390/nu15081874. PMID: 37111092; PMCID: PMC10146730.

5. Ahmad MF, Ahmad FA, Khan MI, Alsayegh AA, Wahab S, Alam MI, Ahmed F. Ganoderma lucidum: A potential source to surmount viral infections through β-glucans immunomodulatory and triterpenoids antiviral properties. Int J Biol Macromol. 2021 Sep 30; 187:769-779. doi: 10.1016/j.ijbiomac.2021.06.122. Epub 2021 Jun 29. PMID: 34197853.

Note: Health Support is compatible with Metabzen by taking 1 Metabzen per day & 3 Health Support capsules.

Maison Jacynthe disclaims all liability. All information contained on this page is not intended to replace justified allopathic treatment or to disregard the expertise of the medical profession. It is up to each individual to take charge of their own health, to inform themselves, and to make the necessary changes to improve their condition. Therapeutic supervision by a qualified healthcare professional is obviously recommended.