Antioxidants neutralize free radicals caused by pollution, poor diet, excessive medication, stress, etc., which are responsible for many disorders, including circulatory or joint problems, skin aging, etc.)
A very powerful antioxidant, Coenzyme Q10 protects cells from oxidative damage and pathogenic bacteria or viruses. It is present in all cells of the body, but the highest concentrations are found in the most energetic organs, including the heart, kidneys, lungs, liver, pancreas, and adrenal glands. Coenzyme Q10 plays an important role in strengthening the immune system and physical performance, as the tissues and cells involved in immune function are highly energy-dependent and therefore require an adequate supply of Coenzyme Q10 for optimal function. 1-2
This energy contributes to:
- Help regenerate the brain, liver, lungs and all vital organs. 2,3
- Maintain your mental abilities and brain health. 3
- Replace your damaged cells with new, healthy cells. 3
- Support your immune system. 4
- Stimulate sperm, which are big consumers of energy. 5
With age, its production declines sharply. At age 50, natural production of Coenzyme Q10 has decreased by 25%, compared to age 25, and by 60% at age 80. 6
Due to its electron charge, the Coenzyme Q10 molecule can neutralize aggressive molecules that attack the body's cells and cause them to age. This is why we see a cumulative effect as we age. From the age of 60, we age more and more rapidly, creating a vicious cycle.
The decrease in the production of Coenzyme Q10, which was initially invisible, leads to a weakening of our natural defense against free radicals. They attack our cells more intensely. As they age, their production of Coenzyme Q10 is further reduced, which exposes them even more to free radicals.
Coenzyme Q10 is a fat-soluble compound that affects the biochemical cascades of the cellular powerhouse, the mitochondria. Mitochondrion produces energy in the form of adenosine triphosphate (ATP: the energy currency of cells) and in fact, nearly 95% of the human body's energy comes from this molecule. Mitochondria play a crucial role in energy metabolism, producing energy at the heart of our cells, and Coenzyme Q10 is a key component of mitochondria. 7-9
Yes, with aging, mitochondria lose their ability to renew themselves. 10
It is suggested that Coenzyme Q10 may have some beneficial effect in the treatment of mitochondrial diseases, and this is mainly based on its ability to restore electron flow in the mitochondrial respiratory chain and replenish cellular antioxidant capacity. 11
References:
1. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter, Molecular Biology of the Cell, 1994, New York, Garland Publishing Inc. ISBN-10: 0-8153-3218-1ISBN-10: 0-8153-4072-9
2. Fujimoto S, Kurihara N, Hirata K, Tak eda T. Effects of coenzyme Q10 administration on pulmonary function and exercise performance in patients with chronic lung diseases. Clin Investig. 1993;71(8 Suppl): S162-6.
3. Ritu A. Shetty, Michael J. Forster, Nathalie Sumien Coenzyme Q10 supplementation reverses age-related impairments in spatial learning and lowers protein oxidation, AGE October 2013, Volume 35, Issue 5, pp 1821-1834
4. Battino M, Bullon P, Wilson M, Newman N. Oxidative injury and inflammatory periodontal diseases: The challenge of antioxidants to free radicals and reactive oxygen species. Crit Rev Oral Biol Med. 1999; 10:458–76.
5. Giancarlo Balercia et al., “Coenzyme Q 10 treatment in infertile men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized trial,” Fertility and sterility 91, no 5 (2009): 1785–1792.
6. Hoppe U, Bergemann J, Diembeck W, Ennen J, Gohla S, Harris I, Jacob J, Kielholz J, Mei W, Pollet D, Schachtschabel D, Sauermann G, Schreiner V, Stäb F, Steckel F. Coenzyme Q10, a cutaneous antioxidant and energizer. Biofactors. 1999;9(2-4):371-8. doi:10.1002/biof.5520090238. PMID: 10416055. https://iubmb.onlinelibrary.wiley.com/doi/abs/10.1002/biof.5520090238?sid=nlm%3Apubmed
7. https://verdictsante.protegez-vous.ca/sante/repertoire-des-produits-de-sante-naturels/coenzyme-q10-coq10#:~:text=La%20CoQ10%20agit%20aussi%20comme,m%C3%AAme%20si%20les%20besoins%20augmentent.
8. https://cordis.europa.eu/article/id/151508-the-role-of-coenzyme-q10/fr#:~:text=La%20coenzyme%20Q10%20est%20un,humain%20provient%20de%20cette%20mol%C3%A9cule.
9. Viruna Neergheen, MSc, Annapurna Chalasani, MSc, Luke Wainwright, MSci, MRes, Delia Yubero, PhD, Raquel Montero, PhD, Rafael Artuch, MD, PhD, and Iain Hargreaves, PhD. Coenzyme Q10 in the Treatment of Mitochondrial Disease, Journal of Inborn Errors of Metabolism & Screening 2017, Volume 5: 1–8 The Author(s) 2017 DOI: 10.1177/2326409817707771 journals.sagepub.com/home/iem https://www.scielo.br/j/jiems/a/khmgpzmBsChfRQ4pgBnjYkL/?format=pdf#:~:text=The%20ability%20of%20CoQ10%20to,and%20replenish%20cellular%20antioxidant%20capacity.
10. Hidalgo-Gutiérrez A, González-García P, Díaz-Casado ME, Barriocanal-Casado E, López-Herrador S, Quinzii CM, López LC. Metabolic Targets of Coenzyme Q10 in Mitochondria. Antioxidants (Basel). 2021 Mar 26;10(4):520. doi:10.3390/antiox10040520. PMID: 33810539; PMCID: PMC8066821. https://pmc.ncbi.nlm.nih.gov/articles/PMC8066821/pdf/antioxidants-10-00520.pdf
11. Saini R. Coenzyme Q10: The essential nutrient. J Pharm Bioallied Sci. 2011 Jul;3(3):466-7. doi:10.4103/0975-7406.84471. PMID: 21966175; PMCID: PMC3178961.
Maison Jacynthe disclaims all liability. All information contained on this page is not intended to replace justified allopathic treatment or to disregard the expertise of the medical profession. It is up to each individual to take charge of their own health, to inform themselves, and to make the necessary changes to improve their condition. Therapeutic supervision by a qualified health professional is obviously recommended.
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